The track list for MUSIC FROM THE MOTION PICTURE: 20th CENTURY WOMEN is peppered with music from the Thirties and Forties, with songs by Benny Goodman and His Orchestra ("In A Sentimental Mood"), Sandy Williams ("After Hours On Dream Street"), and Rudy Vallee and His Connecticut Yankees ("As Time Goes By"). The late-Seventies musical mix highlights American groups like Suicide ("Cheree"), Devo ("Gut Feeling/Slap Your Mammy"), and Germs ("Media Blitz"), as well as English artists like The Raincoats ("Fairytale In The Supermarket"), Siouxsie and the Banshees ("Love In A Void"), and David Bowie ("DJ.")

The soundtrack reflects the film's time period with music from artists who helped define the era. Talking Heads feature prominently on the soundtrack, which includes two of the band's songs: "Don't Worry About The Government" from Talking Heads: 77, the group's debut on Sire Records, and "Big Country," the closing track from the band's 1978 follow-up, More Songs About Buildings and Food.